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CJC-1295 Suppliers: One Name, Two Different Molecules (2026)
Short answer: CJC-1295 is sold under a single commercial name for two structurally different materials, and the certificate of analysis is where a supplier either resolves that ambiguity or leaves it open. For laboratory research use, a CJC-1295 certificate must state which molecule is in the vial, by sequence or by expected mass, before any purity figure on it means anything.
Two distinct materials are sold as CJC-1295; they differ in structure and in expected mass.
The certificate must identify which one, by sequence or expected mass.
A purity figure attached to an unidentified molecule characterises nothing.
Identity by mass spectrometry, purity by RP-HPLC, and net peptide content are three separate statements.
The lot number on the certificate must match the vial.
All materials discussed on this page are supplied for laboratory research use only. They are not for human or veterinary use, not for diagnostic use, and not for any application outside a controlled research setting.
What are the two molecules?
The name CJC-1295 is applied commercially to two things. One is a modified growth-hormone-releasing factor analogue consisting of a 29-amino-acid sequence with substitutions. The other is that same analogue carrying an additional drug affinity complex moiety. They are different molecules with different molecular weights, and in the research literature they are not treated as interchangeable.
The commercial market frequently collapses both into "CJC-1295", sometimes distinguishing them with the suffixes "with DAC" and "without DAC" and sometimes not distinguishing them at all. For a laboratory, that ambiguity is the central documentation problem in this category.
Why identity has to be resolved before purity
Purity is a statement about how much of a sample is the target compound. If the target compound has not been specified, the purity figure has no referent. A certificate reporting a high chromatographic purity for "CJC-1295" without stating which molecule was expected is reporting the purity of something unnamed.
This is why the reading order matters: establish which molecule the certificate claims to characterise, confirm that claim against a measured mass, and only then look at the purity result.
What should a CJC-1295 certificate state?
The specific molecule
Either the full sequence, or the expected molecular mass, or an unambiguous designation that distinguishes the two materials. "CJC-1295" alone is not sufficient.
Identity by mass spectrometry
A measured mass reported against the expected mass for the stated molecule. Because the two candidate molecules differ in mass, this single result also confirms which material is present, which is why it carries unusual weight here.
Purity by RP-HPLC, with the chromatogram
The figure, the retention time, and access to the trace. Ask for the trace; the answer tells you whether the supplier runs testing or forwards documents.
Net peptide content and salt form
Net peptide content is the mass of peptide in the vial as distinct from gross contents, which include counterions, residual solvent and water. The salt form is what explains the gap between those two figures.
Lot traceability and a named laboratory
A lot number matching the vial, and the name of the laboratory that performed the testing. Without both, nothing on the certificate can be independently checked.
How to read a CJC-1295 listing before you order
What the listing or certificate says | What to resolve before ordering |
|---|---|
"CJC-1295" with no further detail | Which of the two molecules; ask for sequence or expected mass |
Purity figure, no stated target molecule | Identity first; the purity figure has no referent yet |
"with DAC" in the title only | Whether the certificate itself states it, not just the product page |
Identity "confirmed", no mass | The measured mass against the expected mass |
Gross vial contents only | Net peptide content and the salt form |
"Third-party tested" | The laboratory's name and the lot reference |
Takeaway: on this compound, the identity line on the certificate matters more than the purity line, because the name on the label does not determine the molecule.
Consistency across the three documents
Check that the product description, the vial label and the certificate all name the same molecule. Disagreement between any two of them is a finding in itself, and it is more common in this category than in most, precisely because the commercial name is ambiguous. A supplier whose three documents agree has demonstrated something about its process beyond the contents of any single result.
Frequently asked questions
What is the difference between CJC-1295 with and without DAC?
They are two different molecules. One is a modified growth-hormone-releasing factor analogue; the other is that analogue carrying an additional drug affinity complex moiety. They differ in molecular weight, so a certificate stating the expected mass also establishes which material is present.
What should a CJC-1295 COA include?
The specific molecule by sequence or expected mass, identity by mass spectrometry against that expected value, chromatographic purity by RP-HPLC with the trace available, net peptide content and salt form, a named testing laboratory, and a lot number matching the vial.
Can I rely on a purity figure if the molecule is not specified?
No. Purity describes how much of a sample is the target compound, so without a stated target the figure has no referent.
How do I check a certificate belongs to my vial?
Match the lot number on the certificate against the lot number printed on the vial, and confirm the testing laboratory is named so the report can be verified with it directly.
This page is documentation guidance for laboratory purchasing and evaluation. All materials referenced are supplied for research use only and are not for human or veterinary use.
