GHK-Cu
Batch #356412
Report #53444
Tested at 99.97% purity
RESEARCH USE ONLY
These compounds are NOT intended for human consumption, clinical use, or veterinary applications. We are not affiliated with any pharmaceutical companies or their commercial medications. By placing an order, you certify these materials will be used exclusively for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
About GHK-Cu
GHK-Cu is a naturally occurring peptide found in human blood plasma urine and saliva. It has been studied for its role in biological processes related to tissue repair cellular signaling and antioxidant activity. Research has explored its potential effects on the skin immune response and cellular regeneration as well as its involvement in mechanisms associated with maintaining tissue health.
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GHK-Cu Research
1. GHK-Cu and Wound Healing
GHK-Cu (glycyl-L-histidyl-L-lysine copper) was initially found in human plasma and it is recognized to have very potent anti-inflammatory and regenerative properties. Studies indicate that this copper-binding peptide can help the body repair itself, as it also kickstarts collagen synthesis, encourages growth of blood vessels and decreases inflammation.
In experiments conducted on animals, GHK-Cu markedly promoted closure of wounds. Topical application of GHK-Cu on full-thickness skin wounds in a rat model yielded an increase in levels of collagen production up to nine times those found for untreated wounds.
Figure A. Increased collagen production in a rat wound healing study with GHK-Cu treatment.
In other experiments in rabbits and in diabetic rats, increased re-epithelization, better organized tissue, and decreased markers of oxidative stress were observed after GHK-Cu treatment. These results suggest its potential effect on promoting faster healing and reducing scar formation.
2. Clinical Research
In a 12-week human trial of GHK-Cu cream on 71 women with photoaged skin, thickness of the skin treated was increased, wrinkles were reduced and clarity was improved over baseline measurement.
Figure A. Skin firmness and wrinkle reduction following 12-week GHK-Cu topical application.
Source: International Journal of Molecular Sciences, 2018.
In a separate 12-week trial with 41 candidates, GHK-Cu eye cream led to significant improvements in skin density and smoothness, exceeding the performance of both vitamin K and placebo creams.
At the cellular level, research has shown that GHK-Cu encourages fibroblasts to create more collagen, elastin, and glycosaminoglycans – all of which are required for beautiful (and young) looking skin! It also regulates matrix-degrading enzymes (MMPs) maintaining the skin's integrity and assist in repair.
3. GHK-Cu in Anti-Aging and Cellular Protection
Besides the contribution to wound-healing action and cosmetics, GHK–Cu exhibits strong antiaging and protectant effects at the human genetic level. Experiments with gene expression analysis show that this peptide has the potential to up-regulate more than 2,000 human genes related to tissue repair, as well as antioxidant and anti-inflammatory pathways.
In cell culture studies, GHK-Cu restored human aged fibroblasts to function as they did when young, increased decorin and integrins (proteins that are necessary for communication of cells). Such capabilities of gene modulation suggest that GHK-Cu not only repairs, but may also reverse cellular aging signs.
4. Safety and Research Outlook
In both preclinical and human research, GHK-Cu has been demonstrated to be extremely safe. It occurs naturally in the body and is well tolerated on topical application for up to 12 weeks.
Although the available data support its cosmetic and regenerative utilities, scientists advise broad clinical trials to validate its medical status in chronic wounds and tissue repair.
Newer technological advancements, such as liposomal and nano-carrier formulations, have improved GHK-Cu stability and skin penetration. Thus, GHK-Cu has emerged as a most favorable bioactive ingredient in regenerative dermatology.
References:
- Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018;19(7):1987. PMC6073405
You ask,
we answer.
Are these peptides quality tested?
Are these peptides quality tested?
Absolutely. Our analytical testing is conducted by Janoshik Analytical, an independent third-party laboratory to verify the identity, purity, and composition of our research products. Each CoA includes purity analysis, peptide sequence confirmation, and date of analysis.
What are typical delivery times?
What are typical delivery times?
Delivery for our free shipping option typically takes 3-5 business days. We ship from right here in the USA to all US addresses. We also provide an option for next day shipping for an extra charge. Please allow 24 hours for processing.
Every package comes with professional packaging, tracking updates via email, and does not require a signature upon delivery.
How should these compounds be stored?
How should these compounds be stored?
Our peptides are shipping in lyophilized form, which is stable at room temperature during transit. Once received, store unopened vials in a cool, dry place.
Are products stable during shipping?
Are products stable during shipping?
Our peptides are shipped in lyophilized (freeze-dried) form, which ensures stability during transit. This powder form is highly stable at room temperature and resistant to temperature fluctuations that occur during shipping.
Research has shown no significant degradation or loss of purity when lyophilized peptides are exposed to room temperature during typical shipping timeframes. Each batch is verified for purity upon production, and our stability testing confirms maintenance of product integrity during standard shipping conditions.
What are your bulk ordering options?
What are your bulk ordering options?
For bulk inquiries and volume pricing, please contact us.
What is your return/refund policy for research peptides?
What is your return/refund policy for research peptides?
All sales are final. Since we're dealing with sensitive research compounds that require strict quality control, we can't accept returns or exchanges.
Questions about your order? We're happy to help - just reach out.
What payment methods do you accept?
What payment methods do you accept?
We accept credit/debit cards, Cash App, and Apple Pay. After you place an order, we'll email you a secure payment link. Please complete payment within 48 hours. Unpaid orders are automatically canceled after that window.
If you don't see the email, check spam/promotion or contact support and we'll resend the link.
Are these peptides legal to buy for research in the USA?
Are these peptides legal to buy for research in the USA?
Yes. When purchased for laboratory/research use only and handled in compliance with all applicable federal, state, and local regulations. We sell reagents labeled “Not for human consumption,” not as drugs or supplements.
Some compounds may be restricted in certain jurisdictions. The buyer is responsible for knowing and following their local rules.
Do I need a business or institutional account to order?
Do I need a business or institutional account to order?
No. Individual researchers, labs, and institutions can order. During checkout you must confirm research intent and agree to our Terms. For certain items or larger orders, we may request additional verification or documentation and reserve the right to decline orders that don’t meet compliance standards.
What is the shelf life/expiration of unopened vials?
What is the shelf life/expiration of unopened vials?
Each lot lists a best-by/expiration on the vial label and COA. As general guidance, lyophilized peptides stored as directed are typically stable 12–24 months (often longer at –20 °C). Short shipping periods at ambient temperature are normal. Actual stability depends on sequence and storage conditions.