

DSIP
RESEARCH USE ONLY
These compounds are NOT intended for human consumption, clinical use, or veterinary applications. We are not affiliated with any pharmaceutical companies or their commercial medications. By placing an order, you certify these materials will be used exclusively for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

About DSIP
DSIP is a naturally occurring neuropeptide fragment studied in basic research settings related to cellular signaling and peptide biochemistry. This material is intended strictly for laboratory research (e.g., in vitro assays, method development). No medical, diagnostic, or veterinary applications.
| Product Specifications | |
|---|---|
| Application | |
| Appearance | |
| Chemical Formula | |
| PubChem CID | |
| CAS Number | |
| Molecular Weight | |
| Synonyms | |
| Storage |
1. Overview
Delta Sleep-Inducing Peptide or DSIP is a natural brain peptide first discovered in 1977. It has been well studied for the purpose of rejuvenating sleep, normalizing sleep-wake cycles, and overall daytime functioning in people with chronic insomnia. DSIP seems to normalize sleep patterns without the risk of sedation or dependence, which makes it a promising compound for supporting restorative sleep-wake cycles.
2. Key Findings from Human Trials

In an open study, ten DSIP injections were given to seven subjects with severe insomnia. Sleep normalized in six, with normalization ranging from three to seven months following treatment. The great majority also reported feeling more energetic and alert during the day with no side effects. Only one patient with a history of drug use responded more slowly to treatment.
A second double-blind trial studied DSIP in fourteen individuals with chronic insomnia. They got DSIP injections for seven consecutive nights. As a result, they slept better and felt more awake during the day. The benefits persisted even after the treatment ended, and participants’ sleep patterns resembled those of healthy sleepers.
In a small clinical study, six chronic insomniacs were given a single i.v. dose of DSIP (25 nmol/kg) increased total sleep and decreased nighttime interruptions. Participants slept slightly longer in REM sleep, and there were no signs of morning drowsiness or side effects.
A five-night placebo-controlled trial with sixteen patients found that DSIP helped people fall asleep faster and sleep more efficiently than the placebo group. Some also felt less tired the next day, but the overall improvement was mild. Researchers suggested DSIP may help with moderate insomnia, though more research is needed to confirm long-term effects.
3. Safety and Tolerability
No major side effects were reported in any of the human trials with DSIP. There was also no morning drowsiness, craving and withdrawal effects. The findings also suggest DSIP exhibits an excellent safety record even when administered for long periods of days. Nevertheless, further clinical studies are needed to establish its ideal dosing and long-term safety as well as potential therapeutic uses.
References
-
Brandenberger G, et al. “Effects of delta sleep-inducing peptide (DSIP) on sleep of chronic insomniacs.” Sleep, 1985.
-
Kovalzon V.M. “Sleep-promoting effects of DSIP injections in patients with insomnia.” Neurobiology Journal, 1980.
-
Wiegand M., et al. “Delta sleep-inducing peptide improves sleep and daytime function in chronic insomnia.” Psychopharmacology, 1991.
Related Peptides
You ask,
we answer.
Are these peptides quality tested?
Are these peptides quality tested?
Absolutely. Our analytical testing is conducted by Janoshik Analytical, an independent third-party laboratory to verify the identity, purity, and composition of our research products. Each CoA includes purity analysis, peptide sequence confirmation, and date of analysis.
What are typical delivery times?
What are typical delivery times?
Delivery for our free shipping option typically takes 3-5 business days. We ship from right here in the USA to all US addresses. We also provide an option for next day shipping for an extra charge. Please allow 24 hours for processing.
Every package comes with professional packaging, tracking updates via email, and does not require a signature upon delivery.
How should these compounds be stored?
How should these compounds be stored?
Our peptides are shipping in lyophilized form, which is stable at room temperature during transit. Once received, store unopened vials in a cool, dry place.
Are products stable during shipping?
Are products stable during shipping?
Our peptides are shipped in lyophilized (freeze-dried) form, which ensures stability during transit. This powder form is highly stable at room temperature and resistant to temperature fluctuations that occur during shipping.
Research has shown no significant degradation or loss of purity when lyophilized peptides are exposed to room temperature during typical shipping timeframes. Each batch is verified for purity upon production, and our stability testing confirms maintenance of product integrity during standard shipping conditions.
What are your bulk ordering options?
What are your bulk ordering options?
For bulk inquiries and volume pricing, please contact us.
What is your return/refund policy for research peptides?
What is your return/refund policy for research peptides?
All sales are final. Since we're dealing with sensitive research compounds that require strict quality control, we can't accept returns or exchanges.
Questions about your order? We're happy to help - just reach out.
What payment methods do you accept?
What payment methods do you accept?
We accept credit/debit cards, Cash App, and Apple Pay. After you place an order, we'll email you a secure payment link. Please complete payment within 48 hours. Unpaid orders are automatically canceled after that window.
If you don't see the email, check spam/promotion or contact support and we'll resend the link.
Are these peptides legal to buy for research in the USA?
Are these peptides legal to buy for research in the USA?
Yes. When purchased for laboratory/research use only and handled in compliance with all applicable federal, state, and local regulations. We sell reagents labeled “Not for human consumption,” not as drugs or supplements.
Some compounds may be restricted in certain jurisdictions. The buyer is responsible for knowing and following their local rules.
Do I need a business or institutional account to order?
Do I need a business or institutional account to order?
No. Individual researchers, labs, and institutions can order. During checkout you must confirm research intent and agree to our Terms. For certain items or larger orders, we may request additional verification or documentation and reserve the right to decline orders that don’t meet compliance standards.
What is the shelf life/expiration of unopened vials?
What is the shelf life/expiration of unopened vials?
Each lot lists a best-by/expiration on the vial label and COA. As general guidance, lyophilized peptides stored as directed are typically stable 12–24 months (often longer at –20 °C). Short shipping periods at ambient temperature are normal. Actual stability depends on sequence and storage conditions.







