Semax
Batch # 190624
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RESEARCH USE ONLY
These compounds are NOT intended for human consumption, clinical use, or veterinary applications. We are not affiliated with any pharmaceutical companies or their commercial medications. By placing an order, you certify these materials will be used exclusively for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
About Semax
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1. Clinical Overview
Semax is a synthetic peptide of adrenocorticotropic hormone (ACTH 4–10) developed in Russia.The drug has a number of nootropic and neuroprotective properties. It has also been clinically proven to improve cognitive performance, stroke rehabilitation, stress adaptation, etc.
2. Human Clinical Findings
Researchers studied how the peptide Semax affected gene activity in stroke-affected animals compared to those that did not receive it, at 3 and 24 hours after a stroke. They found that Semax mainly boosted the activity of genes related to the immune system. Three hours after the stroke, it influenced genes that control immune cell activity, and by 24 hours, this effect became much stronger. More than half of all the genes changed by Semax were linked to immune responses, especially those responsible for producing immunoglobulins and chemokines.
Semax also altered the activity of genes related to the vascular system. Three hours after the stroke, 24 vascular genes were affected, and 12 were affected after 24 hours. These genes are involved in important processes such as blood vessel growth, cell movement, blood formation, and the development of new vessels.
Another randomized controlled trial was conducted. The study included 110 patients with acute ischemic stroke. Thirty patients were administered Semax, a synthetic of ACTG-4-10; the other 80 patients received standard treatment and formed the control group. The recovery assessment was performed with clinical scales, EEG mapping, and evoked potentials testing.
The results indicated a significantly earlier recovery after adding Semax and its beneficial effect on general brain function and motor activity. The most effective daily dose was 12 mg for moderate stage and 18 mg for severe stroke. All the calculations were provided over 5-10 days.
3. Clinical Overview
Furthermore, Semax boosts the expression of brain-derived neurotrophic factor and other molecules of protection for neurons. They promote the survival of neurons and synaptic plasticity; thus, learning and plasticity improves. Semax also balances the work of neurotransmitters involved in mood and the body’s response to stress.
Additionally, by improving oxygen utilization in brain tissue and preventing oxidative damage to neurons, Semax stabilizes the brain during stress, hypoxia, or neurodegenerative processes.
4. Safety & Considerations
Across human trials, Semax has shown an excellent safety profile with no reported toxicity or dependence. Most side effects, if any, are mild and temporary (such as nasal irritation). However, larger international studies are still needed to confirm long-term safety and efficacy outside of Russian populations.
Semax has a good safety profile in all human trials; no toxicity or dependence was reported. In some cases, mild, short-lived side effects such as sore throat and dryness and irritation in the nasal cavity are possible.
References
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Ashmarin IP, et al. Neuroprotective and cognitive effects of Semax in ischemic stroke patients. Human Physiology. 1998.
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Volkov IM, et al. Effect of Semax on attention and memory under stress in healthy volunteers. Neuroscience and Behavioral Physiology. 1999.
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Kolesnikova TO, et al. Semax therapy in children with ADHD: clinical and neurochemical outcomes. Neurosci Behav Physiol. 2007.
Related Peptides
You ask,
we answer.
Are these peptides quality tested?
Are these peptides quality tested?
Absolutely. Our analytical testing is conducted by Janoshik Analytical, an independent third-party laboratory to verify the identity, purity, and composition of our research products. Each CoA includes purity analysis, peptide sequence confirmation, and date of analysis.
What are typical delivery times?
What are typical delivery times?
Delivery for our free shipping option typically takes 3-5 business days. We ship from right here in the USA to all US addresses. We also provide an option for next day shipping for an extra charge. Please allow 24 hours for processing.
Every package comes with professional packaging, tracking updates via email, and does not require a signature upon delivery.
How should these compounds be stored?
How should these compounds be stored?
Our peptides are shipping in lyophilized form, which is stable at room temperature during transit. Once received, store unopened vials in a cool, dry place.
Are products stable during shipping?
Are products stable during shipping?
Our peptides are shipped in lyophilized (freeze-dried) form, which ensures stability during transit. This powder form is highly stable at room temperature and resistant to temperature fluctuations that occur during shipping.
Research has shown no significant degradation or loss of purity when lyophilized peptides are exposed to room temperature during typical shipping timeframes. Each batch is verified for purity upon production, and our stability testing confirms maintenance of product integrity during standard shipping conditions.
What are your bulk ordering options?
What are your bulk ordering options?
For bulk inquiries and volume pricing, please contact us.
What is your return/refund policy for research peptides?
What is your return/refund policy for research peptides?
All sales are final. Since we're dealing with sensitive research compounds that require strict quality control, we can't accept returns or exchanges.
Questions about your order? We're happy to help - just reach out.
What payment methods do you accept?
What payment methods do you accept?
We accept credit/debit cards, Cash App, and Apple Pay. After you place an order, we'll email you a secure payment link. Please complete payment within 48 hours. Unpaid orders are automatically canceled after that window.
If you don't see the email, check spam/promotion or contact support and we'll resend the link.
Are these peptides legal to buy for research in the USA?
Are these peptides legal to buy for research in the USA?
Yes. When purchased for laboratory/research use only and handled in compliance with all applicable federal, state, and local regulations. We sell reagents labeled “Not for human consumption,” not as drugs or supplements.
Some compounds may be restricted in certain jurisdictions. The buyer is responsible for knowing and following their local rules.
Do I need a business or institutional account to order?
Do I need a business or institutional account to order?
No. Individual researchers, labs, and institutions can order. During checkout you must confirm research intent and agree to our Terms. For certain items or larger orders, we may request additional verification or documentation and reserve the right to decline orders that don’t meet compliance standards.
What is the shelf life/expiration of unopened vials?
What is the shelf life/expiration of unopened vials?
Each lot lists a best-by/expiration on the vial label and COA. As general guidance, lyophilized peptides stored as directed are typically stable 12–24 months (often longer at –20 °C). Short shipping periods at ambient temperature are normal. Actual stability depends on sequence and storage conditions.
