FOXO4-DRI

Size: 10mg
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LOT #F4102606-111KCurrent2026-07-13 99.66%

RESEARCH USE ONLY
These compounds are NOT intended for human consumption, clinical use, or veterinary applications. We are not affiliated with any pharmaceutical companies or their commercial medications. By placing an order, you certify these materials will be used exclusively for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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About FOXO4-DRI

FOXO4-DRI (FOXO4 D-Retro-Inverso) is a synthetic research peptide developed for the study of FOXO4–p53 signaling and cellular senescence. It has been investigated as a peptide-based competitor of the FOXO4–p53 interaction, a protein–protein association involved in the survival of certain senescent cell models.

In published preclinical research, disruption of this interaction was associated with p53 nuclear exclusion and activation of apoptosis pathways in senescent cells. Subsequent structural research has further characterized FOXO4-DRI’s direct interaction with the p53 transactivation domain.

FOXO4-DRI is a specialized research material for controlled laboratory studies involving cellular senescence, transcription-factor interactions, and peptide-mediated pathway modulation. Refer to the corresponding batch COA for product-specific analytical data.

For research use only. Not for human or animal consumption. Not for diagnostic or therapeutic use.

Product Specifications

FOXO4-DRI 10mg supplied as lyophilized research material in a sealed vial.

Application

Research use in FOXO4–p53 protein–protein interaction studies, cellular senescence models, p53 localization analysis, and peptide antagonist characterization.

Appearance

Lyophilized material in a sealed glass vial.

Chemical Formula

C228H388N86O64

PubChem CID

167312269

CAS Number

2460055-10-9

Molecular Weight

5358.06 g/mol

Synonyms

FOXO4-DRI, FOXO4 D-Retro-Inverso, FOXO4 DRI, FOXO4-derived retro-inverso peptide, FOX04-DRI

Peptide Sequence

H-ltlrkepaseiaqsileaysqngwanrrsggkrppprrrqrrkkrg-OH (all amino-acid residues in the D-configuration)

Storage

Store lyophilized material at -20°C, sealed, protected from light and moisture.

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