Hexarelin
Batch #514367
Report #53448
Tested at 6.20mg
RESEARCH USE ONLY
These compounds are NOT intended for human consumption, clinical use, or veterinary applications. We are not affiliated with any pharmaceutical companies or their commercial medications. By placing an order, you certify these materials will be used exclusively for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
About Hexarelin
Hexarelin is a synthetic peptide studied for its role in stimulating pathways associated with growth hormone release. Research has explored its interactions with metabolic processes cellular signaling and potential effects on biological systems particularly within the context of peptide activity in the endocrine system.
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Hexarelin Research
1. Clinical Overview
Hexarelin is a synthetic growth hormone, releasing peptide that works to stimulate the release of the natural growth hormone (GH) secretion. The peptide exerts its effect on the (GHS-R1a) ghrelin receptor. Hence, once they are stimulated, more hormone is released and muscle-building, fat metabolism and heart functioning may be improved.
In addition to its effects on growth hormone release, hexarelin has shown potential in influencing other physiological processes. Studies suggest that it may help improve bone density, enhance energy levels, and support tissue repair by increasing the availability of GH and its downstream mediator, IGF-1 (Insulin-like Growth Factor 1).
2. Human Clinical Findings
Six healthy young men were given either two or three daily subcutaneous injection of the peptide hexarelin at a dose of 1.5 micrograms/kg. The levels of hormone were determined every 20 minutes for 24 hours.
Both HEX schedules two (or three daily doses) improved average and total 24-hour growth hormone levels to an equivalent extent. The enhancement was due to enhanced GH concentrations, not from more frequent ones. HEX also prolonged GH half-life in the blood sugar and modified the GH to release hormone synthase pattern more.
Another trial tested how hexarelin, a synthetic peptide that strongly increases growth hormone (GH), affects GH release in eight healthy men aged 21–33 years. Each participant received a single bolus injection of hexarelin (2 micrograms per kilogram) or saline (placebo), both in the morning (8–9 a.m.) after fasting and during sleep (11 p.m.–12 a.m.), in random order.
Blood samples were taken before and every 15 minutes for 2 hours after each injection. GH levels were measured to find peak values and the area under the curve (AUC), showing total GH released.
The study found that peak GH levels after hexarelin were almost the same in the morning (58.2 ± 4.7 μg/L) and during sleep (61.2 ± 4.3 μg/L). However, GH stayed in the blood much longer during sleep (half-life 64.9 ± 14.8 minutes) than in the morning (24.9 ± 1.4 minutes, P < 0.01). The total GH output (AUC) was also significantly higher during sleep (1466 ± 145 μg·min/L) compared to the morning (903 ± 94 μg·min/L, P < 0.001).
3. Mechanism & Effects
Hexarelin binds strongly to GHS-R1a, enhancing GH secretion and increasing downstream IGF-1 levels. Beyond GH release, it shows protective actions on heart muscle cells, improving heart function and reducing damage from oxidative stress. Animal studies also suggest Hexarelin may help preserve bone density and promote lean body mass.
4. Safety & Considerations
Clinical data show Hexarelin is generally well-tolerated. No serious adverse effects were reported in short-term studies. Some subjects experienced mild increases in prolactin and cortisol, which normalized after discontinuation. Long-term studies are limited, so extended use should be approached cautiously.
Additional research notes that Hexarelin’s safety profile remains favorable even with repeated dosing over short treatment periods. Temporary hormonal shifts such as elevated GH, prolactin, and cortisol are typically mild and reversible. Participants in controlled trials did not exhibit cardiac or metabolic complications, and no withdrawal symptoms were observed after stopping the peptide.
References
Ghigo E, et al. Endocrine and metabolic effects of Hexarelin in elderly subjects. Eur J Endocrinol. 1998.
Locatelli V, et al. Cardioprotective properties of Hexarelin in patients with cardiac dysfunction. J Endocrinol Invest. 2000.
You ask,
we answer.
Are these peptides quality tested?
Are these peptides quality tested?
Absolutely. Our analytical testing is conducted by Janoshik Analytical, an independent third-party laboratory to verify the identity, purity, and composition of our research products. Each CoA includes purity analysis, peptide sequence confirmation, and date of analysis.
What are typical delivery times?
What are typical delivery times?
Delivery for our free shipping option typically takes 3-5 business days. We ship from right here in the USA to all US addresses. We also provide an option for next day shipping for an extra charge. Please allow 24 hours for processing.
Every package comes with professional packaging, tracking updates via email, and does not require a signature upon delivery.
How should these compounds be stored?
How should these compounds be stored?
Our peptides are shipping in lyophilized form, which is stable at room temperature during transit. Once received, store unopened vials in a cool, dry place.
Are products stable during shipping?
Are products stable during shipping?
Our peptides are shipped in lyophilized (freeze-dried) form, which ensures stability during transit. This powder form is highly stable at room temperature and resistant to temperature fluctuations that occur during shipping.
Research has shown no significant degradation or loss of purity when lyophilized peptides are exposed to room temperature during typical shipping timeframes. Each batch is verified for purity upon production, and our stability testing confirms maintenance of product integrity during standard shipping conditions.
What are your bulk ordering options?
What are your bulk ordering options?
For bulk inquiries and volume pricing, please contact us.
What is your return/refund policy for research peptides?
What is your return/refund policy for research peptides?
All sales are final. Since we're dealing with sensitive research compounds that require strict quality control, we can't accept returns or exchanges.
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What payment methods do you accept?
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Are these peptides legal to buy for research in the USA?
Are these peptides legal to buy for research in the USA?
Yes. When purchased for laboratory/research use only and handled in compliance with all applicable federal, state, and local regulations. We sell reagents labeled “Not for human consumption,” not as drugs or supplements.
Some compounds may be restricted in certain jurisdictions. The buyer is responsible for knowing and following their local rules.
Do I need a business or institutional account to order?
Do I need a business or institutional account to order?
No. Individual researchers, labs, and institutions can order. During checkout you must confirm research intent and agree to our Terms. For certain items or larger orders, we may request additional verification or documentation and reserve the right to decline orders that don’t meet compliance standards.
What is the shelf life/expiration of unopened vials?
What is the shelf life/expiration of unopened vials?
Each lot lists a best-by/expiration on the vial label and COA. As general guidance, lyophilized peptides stored as directed are typically stable 12–24 months (often longer at –20 °C). Short shipping periods at ambient temperature are normal. Actual stability depends on sequence and storage conditions.